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Science & Technology

Driving the Advancement
of Cutting-edge Science & Technology

Novavax is part of a rich history of innovation to help prevent and treat disease, save lives and improve health. Decades of in-house research has led to the development of our proven proprietary technology platform that is leveraged in marketed products used by people around the globe. 

Improving next generation medicines

Both our protein-based nanoparticles and Matrix-M® adjuvant are the basis of our promising pipeline programs and provide a strong foundation for innovation.
We are working with partners to explore the use of Matrix-M in their pipelines. We are also creating new innovative vaccine candidates with our Matrix-M and nanoparticle technology platforms to facilitate partnership discussions.

In addition, we are expanding the utility of our adjuvant technology by creating additional potential Matrix-based adjuvants including: ​

Adjuvants tailored to foster specific differentiated immune properties for new indications​
Focus on infectious diseases where previous vaccine candidates have been insufficiently immunogenic​
Potential to enable access into new disease areas and indications, including select areas within oncology​
Discover our Matrix-M adjuvant
Discover our technology platform
Our Pipeline

Expanding our efforts in infectious disease and beyond with differentiated programs in areas of unmet need.

Learn more about our pipeline
Discovery Driven by AI & Machine Learning

We leverage a discovery model that is driven by artificial intelligence (AI) and machine learning. This approach enables us to leverage our deep in-house expertise coupled with extensive published scientific literature and modern computational techniques to optimize our product candidates’ efficacy, safety and tolerability. 

Latest Publication
COVID-19, Matrix-M® adjuvant
Real-world effectiveness and safety of protein-based and mRNA COVID-19 vaccines (BEEHIVE trial). Vaccine 2026; 88,128954.
Yoon SK, Phillips AL, Battan-Wraith S, et al.
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Publications

Novavax has been at the forefront of R&D for decades and has contributed a wealth of information to the body of scientific knowledge. Learn more about our science and technology in our publications. 

View our publications